travoprost

Travoprost is a synthetic prostaglandin F2α analog and an ester prodrug used as an ophthalmic solution to lower elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension. After administration as eye drops, it is absorbed through the cornea and hydrolyzed to its active free acid form. The active metabolite acts as a selective agonist at the prostaglandin F receptor (FP) in the eye, increasing aqueous humor outflow via both uveoscleral and trabecular meshwork pathways. This mechanism reduces intraocular pressure and helps prevent optic nerve damage associated with glaucoma. Travoprost is considered highly selective for its target receptor compared to other agents in its class[1][2][3][5][6][8].

Brand names

TravatanTravatan ZIzbaDuotraviDose TR

Other names

Travoprost implantTravoprost insertTravoprost intracameral implantIntracanalicular travoprost insertSustained release travoprost