Drug intelligence / Profile preview

travoprost + latanoprost + bimatoprost

Development stage
Discontinued
Lead developer
Alcon
Modality
Small Molecules
Administration
Ophthalmic
01

Overview

This is not a standard combination therapy. Travoprost, latanoprost, and bimatoprost are three distinct prostaglandin analog medications used to treat glaucoma and ocular hypertension. Each reduces intraocular pressure (IOP) primarily by increasing uveoscleral outflow. Clinical studies have shown that these medications have similar mechanisms of action and comparable efficacy when used individually. While combinations of two prostaglandins (such as bimatoprost added to latanoprost or travoprost added to latanoprost) have shown additive effects in some studies, the use of all three simultaneously is not a standard clinical practice and may not provide additional benefits beyond using just one or two.

Brand names
XalatanTravatanLumigan
Other names
prostaglandin analogues
02

Targets

PTGFR (Prostaglandin F2 alpha receptor)

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