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Drug intelligence / Profile preview
TRC autologous bone marrow cells
- Development stage
- Phase 1
- Lead developer
- Vericel
- Modality
- Stem Cell Therapies → Cell Therapies
- Administration
- Implant
01
Overview
TRC autologous bone marrow cells (Tissue Repair Cells) are a cell-based biologic therapy consisting of autologous bone marrow progenitor cells expanded ex vivo using the Aastrom Replicell™ system. Developed by Aastrom Biosciences (now Vericel), this therapy leverages the osteogenic and regenerative potential of expanded progenitor cells to promote bone healing. The product contains a mixture of stem and progenitor cells, including mesenchymal stem cells and hematopoietic progenitor cells, which contribute to bone formation and vascularization. It has been investigated in Phase I/II clinical trials for the surgical treatment of non-hypertrophic pseudoarthrosis and complex fractures of long bones, demonstrating safety and efficacy in promoting bone callus formation.
- Other names
- Tissue Repair CellsAastrom Tissue Repair Cellsautologous bone marrow progenitor cellsexpanded autologous bone marrow cells
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