tremorine

**Tremorine** is a synthetic small molecule primarily used in scientific research to induce parkinsonian-like tremor in animal models. It is not used therapeutically in humans. Tremorine produces marked tremor, rigidity, and parasympathetic stimulation in animals and is leveraged for the development and screening of anti-Parkinsonian drugs because this drug simulates key features of Parkinson’s disease. Tremorine’s mechanism involves cholinergic pathways, as its effects are reversed by anticholinergic agents such as atropine or scopolamine, and it can increase acetylcholine activity in the nervous system. The drug is significant for its utility in evaluating the efficacy of potential treatments for Parkinson's disease and related motor disorders.[1][4][5][7][10]

Other names

1-(4-pyrrolidin-1-ylbut-2-ynyl)pyrrolidine1,4-dipyrrolidino-2-butyne