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Tret-A is a topical retinoic acid precursor lotion developed by DermAvance. It is designed to be applied to the skin, where it undergoes enzymatic conversion into retinoic acid (tretinoin), the active metabolite of Vitamin A. This metabolic conversion is intended to provide the therapeutic benefits of retinoids, such as the regulation of epithelial cell growth and differentiation, while potentially mitigating the skin irritation and erythema often associated with the direct application of tretinoin. The product is positioned within DermAvance's pipeline for dermatological indications, likely targeting conditions such as acne vulgaris or photoaging.
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