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TrHCROSS is a cross-linked hyaluronic acid (HA) viscosupplement developed by TRB Chemedica for the treatment of knee osteoarthritis. Administered as a single intra-articular injection, it is designed to restore the viscoelasticity of the synovial fluid, which is typically diminished in osteoarthritic joints. The cross-linking of the HA chains increases the molecular weight and residence time of the product within the joint space, providing prolonged lubrication and mechanical cushioning. Clinical evaluation focuses on its safety and efficacy in reducing pain and improving functional outcomes compared to other HA products.
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