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Tri-isoflavones
- Development stage
- Preclinical
- Lead developer
- Natural Pharmacia International
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Tri-isoflavones is a botanical dietary supplement in preclinical development by Natural Pharmacia International (NPI) for the management of postmenopausal symptoms and the prevention of bone loss. The formulation consists of three specific plant-derived isoflavones that function as phytoestrogens. These compounds are designed to act as natural estrogen receptor agonists, mimicking the effects of endogenous estrogen to alleviate symptoms such as hot flashes and to help maintain bone mineral density in postmenopausal women. As a naturally derived product, it is positioned as a potential alternative to traditional hormone replacement therapy.
- Other names
- phytoestrogensisoflavones
02
Targets
PPARA (Peroxisome proliferator-activated receptor alpha)ESR2 (ERβ)PPARG (Peroxisome proliferator-activated receptor gamma)ESR1 (ERα)
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