Drug intelligence / Profile preview

triamcinolone acetonide + lidocaine

Development stage
Preclinical
Lead developer
Apothecon
Modality
Small Molecules
Administration
Intraarticular, Intralesional, Intrabursal, Peritendinous, Soft Tissue Injection
01

Overview

**Triamcinolone acetonide + lidocaine** is a co-packaged injectable combination marketed in the United States as **Omnitrenidol**. It contains triamcinolone acetonide injectable suspension, a synthetic glucocorticoid with anti-inflammatory activity mediated principally through glucocorticoid receptor activation, and lidocaine hydrochloride injection, an amide local anesthetic that reversibly inhibits neuronal ion flux required for impulse initiation and conduction. The kit has been used for intramuscular and intra-articular corticosteroid treatment, including inflammatory rheumatic, allergic, dermatologic, and musculoskeletal conditions, while lidocaine provides immediate local anesthesia. Omnitrenidol was labeled by IT3 Medical as a human prescription-drug kit under an abbreviated new drug application; its NDC is listed as inactive in current labeling resources. ([dailymed.nlm.nih.gov](https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=e31a76e5-719c-4b4d-8bda-5af71a3e377b))

Brand names
Omnitrenidol
Other names
lidocaine + triamcinolone acetonidelidocaine hydrochloride + triamcinolone acetonidetriamcinolone acetonide + lidocaine hydrochloride
02

Targets

SCN1A (Voltage-gated sodium channel protein type 1 subunit alpha)GR (Glucocorticoid receptor)

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