Drug intelligence / Profile preview

triamcinolone acetonide + mepivacaine hydrochloride

Development stage
Unknown
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Administration
Intraarticular
01

Overview

A combination medication consisting of triamcinolone acetonide (a synthetic glucocorticoid corticosteroid) and mepivacaine hydrochloride (a local anesthetic). This combination is administered via intra-articular injection to provide both immediate pain relief and longer-term anti-inflammatory effects for various joint conditions. Mepivacaine provides rapid analgesia (within 45 minutes) while triamcinolone reduces inflammation, edema, and synovial fluid protein concentration. The combination is particularly effective for acute synovitis, gout attacks, and other inflammatory joint conditions.

Brand names
EpirelefanMepecaine 3%
Other names
triamcinolone acetonide + mepivacaine hydrochloride
02

Targets

GR (Glucocorticoid receptor)NaV (Voltage-gated sodium channels)

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