triamcinolone acetonide + nystatin + gramicidin

A topical combination drug that contains **triamcinolone acetonide** (a synthetic corticosteroid with anti-inflammatory and antipruritic effects), **nystatin** (an antifungal polyene that binds to ergosterol in fungal cell membranes, causing increased permeability and cell death), and **gramicidin** (a peptide antibiotic active against gram-positive bacteria by increasing membrane permeability). This combination is used primarily for corticosteroid-responsive skin conditions complicated by secondary bacterial and fungal infections. It acts by reducing inflammation and suppressing immune responses (triamcinolone acetonide), directly killing susceptible fungi (nystatin), and eliminating certain bacteria (gramicidin)[4][9][11][12][13].