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Tribulus terrestris root is a plant-derived extract from the perennial herb Tribulus terrestris, commonly used in traditional medicine systems such as Traditional Chinese Medicine and Ayurveda. The plant is known for its purported aphrodisiac properties and has been traditionally used to treat conditions like sexual dysfunction, chest pain, dizziness, skin and eye disorders, kidney stones, edema, and stomach ailments[1][4][5]. The active constituents include saponins (notably protodioscin), flavonoids, alkaloids, sterols (such as β-sitosterol), and other phytochemicals[8]. Mechanistically, some compounds in Tribulus terrestris may modulate hormone levels or inhibit P-glycoprotein activity in vitro; however clinical relevance of these effects remains unclear[1][4]. It is primarily marketed as an over-the-counter dietary supplement rather than an approved pharmaceutical drug[3].
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