Drug intelligence / Profile preview

TriFol-BD

Development stage
Unknown
Lead developer
Sugen Pharma
Modality
Small Molecules
Administration
Oral
01

Overview

TriFol-BD is a multi-ingredient branded generic nutraceutical product developed and marketed by Sugen Pharma. It is formulated as an oral tablet containing a synergistic combination of the bioactive forms of essential B-vitamins—L-methylfolate, methylcobalamin, and pyridoxal-5-phosphate—alongside biotin and cholecalciferol (Vitamin D3). The product is primarily indicated for pregnancy support, the prevention of neural tube defects (NTDs), and the management of hyperhomocysteinemia. By providing L-methylfolate, the active form of folate that bypasses the MTHFR enzymatic step, TriFol-BD ensures optimal DNA synthesis and fetal neurological development. The addition of methylcobalamin and pyridoxal-5-phosphate supports nerve health and homocysteine metabolism, while biotin and vitamin D3 contribute to maternal metabolic health and bone density maintenance.

Brand names
TriFol-BD
Other names
L-methylfolate + methylcobalamin + pyridoxal-5-phosphate + biotin + cholecalciferol
02

Targets

FOLR1 (FRα)ACC (Acetyl-CoA Carboxylase 1)CBS (Cystathionine beta-synthase)MTR (Methionine synthase)

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