Drug intelligence / Profile preview

Trikatu

Development stage
Phase 3
Modality
Small Molecules
Administration
Oral
01

Overview

Trikatu is a classical Ayurvedic combination drug composed of equal parts dried ginger (Zingiber officinale), black pepper (Piper nigrum), and long pepper (Piper longum). It is primarily indicated as a digestive and metabolic stimulant, widely used as an adjunct to enhance the bioavailability of other herbal medicines. Trikatu exerts its effects by stimulating digestive fire (Agni), promoting nutrient assimilation, improving gastrointestinal motility, and supporting liver, pancreatic, and spleen functions. It is also used for Kapha-related respiratory conditions (such as coughs, colds, asthma, hayfever, and sinus congestion), for weight management (by aiding lipid and toxin metabolism), and for its immunomodulatory and anti-inflammatory actions. Research suggests Trikatu exhibits hepatoprotective properties and can modulate inflammatory and immune responses, supporting its application in conditions such as rheumatoid arthritis and alcoholic liver disease[1][2][3][5][6][7][9].

Brand names
TrikatuTrikatu Churna
Other names
VyoshTryushnaKatutrayaTrikatu Churna
02

Targets

PTGS2 (Prostaglandin-Endoperoxide Synthase 2)CYP2D6 (Cytochrome P450 2D6)CYP3A4 (Cytochrome P450 3A4)

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