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Drug intelligence / Profile preview
Trilagavit
- Development stage
- Phase 3
- Lead developer
- Lagap
- Modality
- Small Molecules
- Administration
- Oral, Intramuscular
01
Overview
Trilagavit is a fixed-dose combination of three essential neurotropic B vitamins: thiamine (vitamin B1), pyridoxine (vitamin B6), and cyanocobalamin (vitamin B12). Developed and marketed by Lagap, it is approved for the prevention and treatment of vitamin B deficiencies and associated neurological disorders. These include neuritis, neuralgia, diabetic polyneuropathy, peripheral neuropathy, sciatica, and herpes zoster. Thiamine, pyridoxine, and cyanocobalamin play synergistic roles in maintaining nervous system health, supporting nerve regeneration, myelin sheath repair, and neurotransmitter synthesis.
- Brand names
- Trilagavit
- Other names
- thiamine + pyridoxine + cyanocobalaminvitamin B1 + vitamin B6 + vitamin B12
02
Targets
MTR (Methionine synthase)MMUT (Methylmalonyl-coenzyme A mutase)PDXK (Pyridoxal kinase)TPK1 (Thiamine pyrophosphokinase 1)
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