Drug intelligence / Profile preview

Trilagavit

Development stage
Unknown
Lead developer
Lagap
Modality
Small Molecules
Administration
Oral, Intramuscular
01

Overview

Trilagavit is a fixed-dose combination of three essential neurotropic B vitamins: thiamine (vitamin B1), pyridoxine (vitamin B6), and cyanocobalamin (vitamin B12). Developed and marketed by Lagap, it is approved for the prevention and treatment of vitamin B deficiencies and associated neurological disorders. These include neuritis, neuralgia, diabetic polyneuropathy, peripheral neuropathy, sciatica, and herpes zoster. Thiamine, pyridoxine, and cyanocobalamin play synergistic roles in maintaining nervous system health, supporting nerve regeneration, myelin sheath repair, and neurotransmitter synthesis.

Brand names
Trilagavit
Other names
thiamine + pyridoxine + cyanocobalaminvitamin B1 + vitamin B6 + vitamin B12
02

Targets

TPK1 (Thiamine pyrophosphokinase 1)MTR (Methionine synthase)MMUT (Methylmalonyl-coenzyme A mutase)PDXK (Pyridoxal kinase)

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