trimebutine (Hainan Poly Pharmaceuticals)

Nuowei is a brand name for trimebutine maleate, a gastrointestinal motility regulator developed by Hainan Poly Pharm. It acts as a non-selective agonist of peripheral mu, delta, and kappa opioid receptors in the gastrointestinal tract. Trimebutine is used to treat functional bowel disorders, including irritable bowel syndrome (IBS), by modulating intestinal motility—acting as an antispasmodic in hypermotile states and a prokinetic in hypomotile states. It also interacts with voltage-gated ion channels and has local anesthetic properties. The drug is primarily indicated for the symptomatic treatment of pain, transit disturbances, and intestinal discomfort related to functional bowel disorders.

Brand names

NuoweiDebridat

Other names

trimebutine maleate