Drug intelligence / Profile preview

Trimix

Development stage
Phase 3
Lead developer
Off Health
Modality
Liposomes → Lipid-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Small Molecules
Administration
Ophthalmic
01

Overview

Trimix is a multi-action ophthalmic formulation developed by Off Health Italia, designed to treat dry eye disease (DED). It combines viscosity-enhancing hyaluronic acid, trehalose, and cationic liposomes comprising stearylamine and phospholipids. This combination aims to disrupt the DED vicious cycle by improving tear film stability, providing mechanical protection and lubrication to ocular surface cells, protecting against desiccation and oxidative damage, accelerating corneal healing, reducing inflammation, and restoring osmotic balance. The cationic liposomes specifically replenish and stabilize the lipid layer of the tear film, enhancing its thickness and spreading on the ocular surface.

Brand names
Trimix
Other names
Trimix formulationTrimix eye drop

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