triple needle

**Triple needle** is an investigational intra-articular treatment regimen for early and mid-stage knee osteoarthritis consisting of betamethasone, lidocaine, and sodium hyaluronate. In the registered ChiCTR2100048131 study, the initial injection contained 0.3 mL betamethasone, 0.7 mL lidocaine, and 2 mL sodium hyaluronate, followed by four weekly sodium hyaluronate injections. Betamethasone provides local glucocorticoid anti-inflammatory activity, lidocaine provides rapid local analgesia through neuronal sodium-channel blockade, and sodium hyaluronate provides intra-articular viscosupplementation. ([pmc.ncbi.nlm.nih.gov](https://pmc.ncbi.nlm.nih.gov/articles/PMC12971529/))

Other names

triple injection三联针