tripterygium wilfordii complex ester

Tripterygium wilfordii complex ester is a botanical drug preparation derived from the leaves (Folium) of the *Tripterygium wilfordii* Hook. f. plant, commonly known as Thunder God Vine. While traditional preparations of this plant typically utilize the root, the complex ester formulation specifically uses the leaves to extract active diterpenoids and alkaloids. It is primarily used in the treatment of rheumatoid arthritis and other autoimmune or inflammatory diseases. The drug exerts its therapeutic effects through potent immunosuppressive and anti-inflammatory actions, including the inhibition of pro-inflammatory cytokine production (such as TNF-α, IL-1, and IL-6), suppression of T-cell proliferation, and modulation of the NF-κB signaling pathway. Clinical studies have shown it to have comparable efficacy and safety to the more common root-derived polyglycoside preparations.

Other names

Folium Tripterygium wilfordii preparationTripterygium wilfordii leaf extractTripterygium Wilfordii Complex Ester Tablet