Drug intelligence / Profile preview

TROCEPT-02

Development stage
Preclinical
Lead developer
Accession Therapeutics
Modality
Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, Viral Vectors → Gene Addition/Replacement → Gene Therapies
Administration
Intratumoral, Intravenous
01

Overview

TROCEPT-02 is an investigational cancer therapy developed by Accession Therapeutics. It utilizes a unique viral technology platform (TROCEPT) to deliver a universal bispecific antibody payload that targets both tumor and stromal cells. The therapy is designed so that, once the virus infects cancer cells, it induces production and secretion of the bispecific antibody directly within the tumor microenvironment, potentially enhancing anti-tumor efficacy while limiting systemic exposure. TROCEPT-02 is expected to enter clinical trials in 2026[1][2]. The approach aims to transform outcomes for cancer patients by enabling localized production of potent biologic drugs inside tumors.

02

Targets

MAGEA8 (Melanoma-associated antigen 8)

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