Troxipide

Troxipide is a small molecule drug classified as a non-antisecretory gastric cytoprotective agent with anti-ulcer, anti-inflammatory, and mucus-secreting properties. It is primarily used for the treatment of peptic ulcers, gastroesophageal reflux disease (GERD), acute gastritis, and acute exacerbation of chronic gastritis. Unlike traditional antiulcer drugs that reduce gastric acid secretion or neutralize acid, troxipide acts by fortifying the gastric mucosal barrier through increased synthesis of glucosamine, mucopolysaccharides, and collagen. It also stimulates the release of cytoprotective prostaglandins (notably PGE2 and PGD2), enhances mucosal blood flow and metabolism, increases mucus production and glycoprotein excretion in the gastric mucosa, inhibits neutrophil-mediated inflammation and oxidative stress in the stomach lining. Troxipide’s protective effects are independent of stomach pH[1][4][5][6].

Brand names

Troxipide

Other names

3,4,5-trimethoxy-N-(3-piperidyl)benzamide