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TRPV3 inhibitor (Salipro Biotech) is a preclinical-stage therapeutic candidate being developed by Salipro Biotech for the treatment of CNS-related pain. The program targets the Transient Receptor Potential Vanilloid 3 (TRPV3) ion channel, a calcium-permeable non-selective cation channel involved in thermosensation and nociception. Salipro Biotech utilizes its proprietary Salipro® technology to stabilize the multi-pass transmembrane TRPV3 protein in a native-like lipid environment, which facilitates the discovery and development of potent and selective modulators. By inhibiting TRPV3 activity in the central nervous system, the drug aims to provide a novel analgesic approach for managing chronic pain conditions.
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