Drug intelligence / Profile preview

TSA-CTL

Development stage
Phase 1
Lead developer
BGI
Modality
TCR-Engineered T Cells → Engineered T Cells → Adoptive Cell Transfer → Cell Therapies
Administration
Intravenous
01

Overview

TSA-CTL is a form of adoptive cell therapy that uses cytotoxic T lymphocytes engineered to target tumor-specific antigens. The therapy involves collecting a patient's T cells, engineering them to recognize tumor-specific antigens, and then reinfusing these cells back into the patient to target and kill cancer cells. It is being investigated for the treatment of advanced solid tumors, particularly melanoma.

Other names
Tumor Specific Antigen-Cytotoxic T Lymphocyte

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