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TSHA-115
- Development stage
- Preclinical
- Lead developer
- Taysha Gene Therapies
- Modality
- Gene Therapies
- Administration
- Not Disclosed (gene Therapies Are Typically Intravenous, Intrathecal, Or Intramuscular Based On The Indication, But This Is Not Specified For TSHA-115)
01
Overview
TSHA-115 is an investigational **gene therapy** developed by Taysha Gene Therapies for the treatment of **glycogen storage diseases**. It is designed to utilize a microRNA (miRNA)-regulated delivery system to provide therapeutic benefit in affected tissues[9][11]. The specific genetic modification, target gene(s), and underlying mechanism are not fully public, but based on Taysha’s general platform, TSHA-115 likely uses an **adeno-associated virus (AAV) vector** system for gene delivery and regulation in metabolic disease tissues. These features may allow for tissue-selective expression and reduced off-target effects, though details remain preclinical.
- Brand names
- TSHA-115TSHA115TSHA 115
- Other names
- TSHA-115TSHA115TSHA 115
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