Drug intelligence / Profile preview

TSP4 monoclonal antibody

Development stage
Unknown
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
01

Overview

TSP4 monoclonal antibody refers to a class of monoclonal antibodies designed to target and inhibit thrombospondin-4 (TSP4), a calcium-binding extracellular matrix glycoprotein. TSP4 is implicated in tissue remodeling, cell adhesion, migration, and vascular inflammation, and is upregulated in various cancers (such as bladder cancer) and neuropathic pain conditions. By blocking TSP4, these antibodies can inhibit lymphatic endothelial cell recruitment, lymphangiogenesis, and tumor metastasis, as well as potentially alleviate neuropathic pain.

Other names
TSP4 mAbTSP-4 mAbTSP 4 mAbanti-TSP4 monoclonal antibodyanti-TSP-4 monoclonal antibodyanti-TSP 4 monoclonal antibodyanti-thrombospondin-4 monoclonal antibodyanti-thrombospondin4 monoclonal antibodyanti-thrombospondin 4 monoclonal antibodythrombospondin-4 mAbthrombospondin4 mAbthrombospondin 4 mAbthrombospondin-4 monoclonal antibodythrombospondin4 monoclonal antibodythrombospondin 4 monoclonal antibody
02

Targets

THBS4 (Thrombospondin-4)

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