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**TT-601** is a discontinued small molecule drug candidate that acts as a potent and selective ligand for a novel nuclear receptor target. It was initially developed by Eli Lilly & Co. for potential use in treating osteoarthritis pain by modulating the activity of this target. The program was later acquired by Transition Therapeutics Inc., but development has been discontinued, with no further clinical advancement reported in nervous system diseases or skin and musculoskeletal disorders.[7][10][13]
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