Drug intelligence / Profile preview

Tualang honey

Development stage
Phase 3
Administration
Oral, Topical
01

Overview

Tualang honey is a Malaysian multifloral jungle honey produced by the rock bee (Apis dorsata), which builds hives on branches of tall Tualang trees primarily in northwestern Peninsular Malaysia. This natural product has gained significant attention in medical research due to its numerous therapeutic properties. Tualang honey possesses a wide range of medicinal properties that have been documented in scientific studies, including **Antioxidant Activity** (rich in flavonoids and phenolic acids protecting against DNA damage and oxidative stress), **Antimicrobial Properties** (strong antibacterial activity against various common bacteria like E. coli, Streptococcus, Salmonella, S. aureus, and P. aeruginosa, particularly effective against gram-negative bacteria in burn wounds), **Anti-inflammatory Effects** (contributes to wound healing by easing inflammation), **Anticancer Potential** (inhibitory effects on breast and cervical cancer cells, potential supplement to conventional treatments), **Wound Healing** (promotes new cell growth, prevents burn wound infections), **Neuroprotective Effects** (boosting cognition, memory, relieving stress, antidepressive effects), **Metabolic Benefits** (improves hypertension, lipid profiles, and diabetes in rats; decreases diastolic blood pressure and fasting blood sugar in postmenopausal women), and **Reproductive Health** (improves sperm parameters, erectile function, and hormonal profiles in oligospermic males).

02

Targets

PTPN11 (Tyrosine-protein phosphatase non-receptor type 11)PIK3CA (Phosphoinositide 3-kinase alpha)PIK3R1 (Phosphoinositide-3-kinase regulatory subunit 1)EGFR T790M (Epidermal growth factor receptor T790M mutant)AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)

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