tulobuterol

Tulobuterol is a long-acting beta2-adrenergic receptor agonist used primarily as a bronchodilator for the management of asthma and chronic obstructive pulmonary disease (COPD). It works by selectively stimulating beta2-adrenergic receptors in bronchial smooth muscle, leading to muscle relaxation and airway dilation. This results in improved airflow and relief from symptoms such as wheezing, shortness of breath, and chest tightness. Tulobuterol is notable for its availability as a transdermal patch (Hokunalin tape), which provides sustained drug delivery over 24 hours with once-daily application. The patch formulation helps synchronize peak blood concentrations with periods of greatest need (e.g., morning dip in respiratory function) while minimizing systemic side effects[1][3][8]. Oral tablet forms are also available in some regions[6]. Tulobuterol has been approved since 1998 in Japan and is marketed in several countries including Japan, Germany, China, South Korea, Bangladesh, Pakistan, Venezuela, and India[3][8].

Brand names

Hokunalin tapeTulobuterol TapeTULOBUTEROL TAPE 2mg "NP"TULOBUTEROL TAPE 2mg "YP"

Other names

tulobuterol hydrochloride