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tumor antigen-sensitized dendritic cell vaccine (West China Hospital)

Development stage: Unknown
Lead developer: Sichuan University
Modality: Dendritic Cell Vaccines → Immune Effector Cells → Other Cell Types → Cell Therapies, Vaccines & Immunotherapeutics
Administration: Subcutaneous

Overview

The tumor antigen-sensitized dendritic cell vaccine developed by West China Hospital is an autologous cell-based immunotherapy designed as an adjuvant treatment for patients with colorectal cancer liver metastases following R0 resection. The vaccine is produced by harvesting a patient's dendritic cells and sensitizing them with tumor-associated antigens. Once administered subcutaneously, these mature, antigen-presenting dendritic cells are intended to activate the patient's immune system, specifically cytotoxic T lymphocytes, to recognize and eliminate residual micrometastatic colorectal cancer cells, thereby reducing the risk of recurrence.

Other names: Tumor antigen-sensitized DC vaccineTumor Antigen-sensitized DC Vaccine for Colorectal Cancer Liver Metastases

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