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Tumor Treatment Vaccine

Development stage
Preclinical
Lead developer
Wuxi People's Hospital
Modality
Vaccines & Immunotherapeutics
Administration
Subcutaneous
01

Overview

**Tumor Treatment Vaccine** is an investigational, complex bacterial immunotherapy developed by Wuxi People's Hospital for relapsed and refractory advanced solid tumors. The product contains bacterial vaccine components from *Bordetella pertussis*, typhoid/paratyphoid A/B organisms, and *Staphylococcus aureus*, together with diphtheria and tetanus toxoid components and immunostimulatory adjuvants including polyinosinic-polycytidylic acid, glucan, and fat emulsion. It is intended to induce broad innate and adaptive antitumor immune activation rather than selectively inhibit a single tumor target. Wuxi People's Hospital has registered studies of TTV, including Neo-BCV as an alternative name, as monotherapy and in combination with PD-1 or PD-L1 inhibitors for recurrent, refractory advanced solid tumors. ([clinicaltrials.gov](https://clinicaltrials.gov/study/NCT06430502))

Other names
Neo-BCVTTVtumor treatment vaccine injectiontumour treatment vaccine
02

Targets

TLR3 (Toll-like receptor 3)

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