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TumorSelect Paclitaxel
- Development stage
- Preclinical
- Lead developer
- Cloaked Therapeutics
- Modality
- Small Molecules
- Administration
- Intravenous
01
Overview
**TumorSelect Paclitaxel** is a targeted formulation of the taxane chemotherapy agent paclitaxel, designed for tumor-selective delivery to enhance efficacy and reduce systemic toxicity. Paclitaxel stabilizes microtubules, preventing depolymerization and disrupting mitotic spindle function, leading to G2/M phase arrest and apoptosis in rapidly dividing cancer cells. Developed as a novel delivery system, it aims to concentrate the drug at the tumor site for improved therapeutic outcomes in solid tumors.
- Brand names
- TumorSelect Paclitaxel
- Other names
- TumorSelect nanoparticle-delivered paclitaxelLDL-mimicking nanoparticle paclitaxelTumorSelect-Paclitaxel-Cloaked Therapeutics-nanoparticle drug delivery (LDL-mimicking nanoparticle)-chemotherapy (paclitaxel)-cancer-oncology
02
Targets
TUBB (Tubulin (alpha and beta subunits))BCL-2 (BCL-2 family)
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