Drug intelligence / Profile preview

tunicatachalcone

Development stage
Unknown
Lead developer
Hebei Medical University
Modality
Small Molecules
01

Overview

tunicatachalcone: sourced facts only. name: "A strong binding between TC and RIPK2 was further demonstrated based on the results of SPR, MST and molecular modeling." [PMID:35792403]; target: "A strong binding between TC and RIPK2 was further demonstrated based on the results of SPR, MST and molecular modeling." [PMID:35792403]; developer: "School of Pharmaceutical Sciences, Hebei Medical University, 050017 Shijiazhuang, China." [PMID:35792403]; modality: "TC is a natural chalcone compound derived from Pongamia pinnata, a medicinal plant." [PMID:35792403]; stage: "The results revealed that TC (5-20 μM) ameliorated the activation of BV-2 microglia induced by lipopolysaccharide (LPS) in a dose-dependent way, which was proved by the reduced production of inflammation-related mediators." [PMID:35792403]

02

Targets

RIPK2 (Receptor-interacting protein serine/threonine kinase 2)

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