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Tuo Li Xiao Du San is a traditional Chinese medicine (TCM) herbal formula traditionally used to treat chronic, non-healing sores and carbuncles. It is designed to "tonify the interior and express toxins," effectively supporting the body's Qi and blood to promote the discharge of pus and the regeneration of tissue. The standard formula consists of twelve herbs, including *Astragalus membranaceus*, *Angelica sinensis*, and *Lonicera japonica*. In modern clinical research, it is being evaluated for its efficacy in promoting wound healing following anal fistula surgery and as a palliative treatment for patients with bone metastases to reduce skeletal-related events and improve survival. Some clinical studies utilize modified versions, such as a special four-herb formula, while maintaining the core therapeutic principles of the original prescription.
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