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Turmeric + curcumin complex is a **dietary supplement** composed of an extract from the root of Curcuma longa (turmeric) and its primary bioactive component, curcumin. These formulations often contain a high percentage of standardized curcuminoids (such as 95% curcumin extract) and may include absorption enhancers like piperine (BioPerine) from black pepper. Turmeric has been used for centuries in traditional medicine for its **anti-inflammatory, antioxidant, antimicrobial, immunoregulatory, chemopreventive, and analgesic effects**. Curcumin's mechanism of action includes modulating several molecular targets involved in inflammation, oxidative stress, and cellular signaling, such as **inhibition of cyclooxygenase (COX), inducible nitric oxide synthase (iNOS), lipoxygenase, xanthine oxidase, protein kinase C (PKC), tyrosine kinase, NF-κB**, and many others. These supplements are primarily used for joint support, wellness, and as adjuncts for managing chronic inflammatory and metabolic conditions.
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