Drug intelligence / Profile preview

turmeric extract cream

Development stage
Preclinical
Modality
Small Molecules, Transdermal Patches → Device-based Delivery → Drug Delivery Systems, Hydrogel Systems → Drug Delivery Systems
Administration
Topical
01

Overview

Turmeric extract cream is a topical formulation containing extracts from the rhizome of Curcuma longa (turmeric), primarily standardized for curcuminoids such as curcumin. It is used in dermatology and alternative medicine for its anti-inflammatory, antioxidant, antibacterial, and wound-healing properties. Topical application has been studied for conditions like atopic dermatitis and inflammatory skin disorders; some studies suggest it may reduce erythema, scaling, thickening, itching, facial spots, fine lines, and wrinkles[9]. The mechanism of action is thought to involve inhibition of NF-κB activation and downstream pro-inflammatory mediators. Turmeric’s active compounds also exhibit antimicrobial effects that may benefit infected wounds or acne[8][6]. While generally considered safe when applied to the skin[1][3], rare allergic reactions (contact dermatitis) have been reported[10].

Other names
turmeric creamtopical turmericcurcumin cream
02

Targets

PTGS2 (Prostaglandin-Endoperoxide Synthase 2)NF-κB

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