Drug intelligence / Profile preview

Tussilene

Development stage
Unknown
Lead developer
Laboratórios Azevedos
Modality
Small Molecules
Administration
Oral
01

Overview

Tussilene is a brand name used by Laboratórios Azevedos for a family of non-prescription (over-the-counter) cough and cold medications marketed primarily in Portugal. The product line consists of several monotherapies designed to address different types of cough and respiratory symptoms. These include Acetilcisteína Tussilene (acetylcysteine), which serves as a mucolytic to fluidize thick mucus in productive coughs; Ambroxol Tussilene (ambroxol), which acts as a secretolytic and expectorant to facilitate mucus clearance; and Dextrometorfano Tussilene (dextromethorphan), a non-opioid antitussive that acts on the central nervous system to suppress dry, irritating, non-productive coughs. The products are available in oral formulations such as syrups, oral solutions, and effervescent tablets.

Brand names
Acetilcisteína TussileneAmbroxol TussileneBromexina TussileneDextrometorfano TussileneTussilene
Other names
Tussilene Effervescent TabletsTussilene Oral SolutionTussilene Syrup
02

Targets

GRIN1 (NMDA receptor subunit 1)GRIN2A (NMDA receptor subunit 2A)MUC5AC (Mucin-5AC)NMDAR (Glutamate receptor ionotropic, NMDA)SCN10A (Sodium channel protein type X alpha subunit)SCN9A (Sodium channel protein type 9 subunit alpha)SIGMAR1 (Sigma non-opioid intracellular receptor 1)SLC7A11 (Cystine-Glutamate Antiporter)GBA1 (Glucosylceramidase)

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