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TV-100 is a monoclonal antibody in preclinical development by TheraVac Biologics. It is designed as an inflammasome-blocking agent, intended to inhibit the activation of the inflammasome complex. By blocking the inflammasome, the drug aims to prevent the maturation and secretion of pro-inflammatory cytokines, which are key drivers in various inflammatory and neurodegenerative diseases. While TheraVac's other pipeline assets, such as TV-301 and TV-202, are virus-like particle (VLP) vaccines targeting specific components like NLRP3 and ASC, the specific molecular target for TV-100 has not been explicitly disclosed beyond its general classification as an inflammasome blocker.
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