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Twin block

Development stage: Unknown
Modality: Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Administration: Injection

Overview

Twin block, in the context of a drug, refers to a local anesthetic nerve block injection. This injection involves the administration of standard dental numbing medication to specifically target and numb the jaw-clencher muscles, namely the masseter and temporalis. It is utilized for pain management, particularly to alleviate acute post-operative pain following third molar extractions and to treat chronic myofascial pain. The primary objective of its use is to provide effective pain relief and consequently reduce the need for opioid prescriptions.

Other names: Temporo-masseteric Nerve Block

Targets

NaV (Voltage-gated sodium channels)

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