Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
Twirla
- Development stage
- Approved
- Lead developer
- Insud Pharma
- Modality
- Small Molecules
- Administration
- Transdermal
01
Overview
Twirla (AG-200-15) is a combined hormonal contraceptive (CHC) transdermal patch developed by Agile Therapeutics. It is designed to deliver a daily dose of 120 mcg of levonorgestrel (a progestin) and 30 mcg of ethinyl estradiol (an estrogen) over a seven-day period. The patch utilizes the proprietary Skinfusion technology, which consists of multiple layers designed to provide effective hormone delivery while maintaining adhesion and comfort. Its primary mechanism of action is the suppression of gonadotropins, which inhibits ovulation. Additionally, it induces changes in the cervical mucus (increasing viscosity to prevent sperm penetration) and the endometrium (reducing the likelihood of implantation). It is indicated for use by women of reproductive potential with a body mass index (BMI) less than 30 kg/m², as its efficacy may be reduced in women with higher BMIs.
- Brand names
- Twirla
- Other names
- levonorgestrel + ethinyl estradiol transdermal system
02
Targets
AR (Adrenergic receptors)ER (Estrogen receptor)PR (Progesterone receptor)
Beyond the preview
Go deeper on Twirla.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Twirla.