Drug intelligence / Profile preview

Tylofas Forte

Development stage
Unknown
Lead developer
Zakfas Pharmaceuticals
Modality
Small Molecules
Administration
Oral
01

Overview

**Tylofas Forte** is a marketed veterinary fixed-dose antimicrobial product manufactured by Zakfas Pharmaceuticals. Each mL contains tylosin tartrate 50 mg, colistin sulfate 10 mg, and dimetridazole 100 mg. Tylosin is a macrolide antibacterial that inhibits bacterial protein synthesis through the 50S ribosomal subunit; colistin is a polymyxin antibacterial that disrupts the outer membrane of susceptible Gram-negative bacteria through lipopolysaccharide binding; and dimetridazole is a nitroimidazole antiprotozoal and antibacterial agent that is reduced in anaerobic organisms to reactive metabolites that damage DNA. The public product listing does not specify the labeled animal species, indications, administration route, or dosage regimen.

Brand names
Tylofas Forte
02

Targets

MurA (UDP-N-acetylglucosamine 1-carboxyvinyltransferase)Bacterial 50S ribosomal subunit

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