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Typhocon
- Development stage
- Phase 2
- Lead developer
- Incepta Vaccine
- Modality
- Vaccines & Immunotherapeutics
- Administration
- Intramuscular
01
Overview
Typhocon is a typhoid conjugate vaccine (TCV) developed and manufactured by Incepta Vaccine Limited. It is composed of the Vi capsular polysaccharide of *Salmonella typhi* covalently conjugated to a diphtheria toxoid (DT) carrier protein. This conjugation transforms the T-cell independent Vi polysaccharide antigen into a T-cell dependent antigen, which significantly enhances immunogenicity, particularly in infants and young children, and induces long-term immunological memory. Typhocon is designed to prevent typhoid fever in individuals ranging from 6 months to 60 years of age. In clinical studies, it has been evaluated for non-inferiority in safety and immunogenicity compared to the WHO-prequalified reference vaccine Typbar-TCV.
- Brand names
- Typhocon
- Other names
- Vi-DTTyphoid Vi polysaccharide-diphtheria toxoid conjugate vaccineVi-DT vaccine
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