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Typhoid conjugate vaccine (Indian Immunologicals)
- Development stage
- Preclinical
- Lead developer
- Indian Immunologicals
- Modality
- Vaccines & Immunotherapeutics
- Administration
- Intramuscular
01
Overview
The Typhoid Conjugate Vaccine (TCV) developed by Indian Immunologicals is a monovalent vaccine designed to provide long-lasting protection against typhoid fever caused by *Salmonella Typhi*. Unlike traditional polysaccharide vaccines, this conjugate vaccine chemically links the Vi capsular polysaccharide of the bacterium to a carrier protein. This conjugation process enhances the immune response by engaging T-cells, which allows for the induction of immunological memory and makes the vaccine effective in infants and young children. The vaccine is currently in advanced stages of clinical development in India.
- Other names
- TCVTyphoid conjugate vaccine
02
Targets
Vi polysaccharide-specific B-cell receptor
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