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typhoid fever vaccine + Advax
- Development stage
- Preclinical
- Lead developer
- Vaxine
- Modality
- Recombinant Proteins and Enzymes, Vaccines & Immunotherapeutics
- Administration
- Intramuscular
01
Overview
typhoid fever vaccine + Advax is a recombinant protein subunit vaccine candidate being developed by Vaxine for the prevention of typhoid fever. The vaccine consists of recombinant Salmonella typhi antigens formulated with Advax, a proprietary adjuvant platform based on delta-inulin. Advax is designed to enhance both humoral and cellular immune responses, including the induction of high-titer antibodies and T-cell activation, while maintaining a high safety profile without the inflammatory side effects often associated with traditional adjuvants. The vaccine is currently in the preclinical stage of development.
- Other names
- protein + Advax typhoid vaccineSalmonella typhi protein vaccine
02
Targets
Vi antigen (Vi capsular polysaccharide)TLR9 (Toll-like receptor 9)
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