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This antioxidant therapy refers to a specific multi-component nutritional regimen evaluated by the University of Guadalajara in clinical trials for non-proliferative diabetic retinopathy (NPDR). The therapy typically involves the administration of ubiquinone (Coenzyme Q10) alongside a combined antioxidant supplement containing Vitamin E (alpha-tocopherol), Vitamin C (ascorbic acid), Beta-carotene, Zinc, Copper, and Selenium. The mechanism of action centers on mitigating oxidative stress and mitochondrial dysfunction, which are critical factors in the progression of retinal microvascular damage in diabetic patients. By scavenging reactive oxygen species (ROS) and providing essential cofactors for endogenous antioxidant enzymes like superoxide dismutase and glutathione peroxidase, the treatment aims to preserve retinal integrity and slow the progression of NPDR.
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