ufenamate

Ufenamate is a non-steroidal anti-inflammatory drug (NSAID) designed for topical application to treat various inflammatory and pruritic skin conditions. Marketed by Miyarisan Pharmaceutical in Japan under the brand name Dermaclin, it is indicated for conditions such as eczema, dermatitis, diaper rash, and shingles-associated pain. Ufenamate functions by inhibiting the synthesis of prostaglandins, which are key mediators of inflammation and itching. Unlike topical corticosteroids, ufenamate does not typically cause skin atrophy or other steroid-related side effects, making it a preferred option for sensitive skin areas or pediatric use in conditions like diaper dermatitis.

Brand names

DermaclinDermaclin A

Other names

butyl 2-((3-(trifluoromethyl)phenyl)amino)benzoateufenamato