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UHE-101 is a small molecule drug developed by Therapeutics, Inc. for dermatological use, specifically as a topical cream formulation. Its primary indication is the treatment of acne vulgaris. The drug has been evaluated in at least one Phase 2 clinical trial as a 1% cream applied topically twice daily for 12 weeks in subjects with facial acne vulgaris. The mechanism of action and molecular target have not been publicly disclosed. As of the latest update, its highest global R&D status is "Pending," and it has not received regulatory approval[1].
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