Drug intelligence / Profile preview

UI123

Development stage
Preclinical
Lead developer
Korea United Pharm
Modality
Small Molecules
01

Overview

UI123 is a Korea United Pharm small-molecule incrementally modified drug candidate being developed as a new fixed-dose combination lipid-modifying therapy. The company’s pipeline places UI123 in formulation development and identifies it as a long-term lipid-modifying-agent program; its active constituents, pharmacologic targets, dosage form, route of administration, and detailed mechanism have not been publicly disclosed. ([kup.co.kr](https://www.kup.co.kr/research/pipeline/pipeline02.htm))

Brand names
Atorax-E
Other names
atorvastatin and ezetimibe combination
02

Targets

HMGCR (3-hydroxy-3-methylglutaryl-coenzyme A reductase)NPC1L1 (Niemann-pick C1-Like 1 transporter)

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