UM-STAT3-1218

UM-STAT3-1218: sourced facts only. name: "Taken together, (UM-STAT3-1218) is a highly promising STAT3 degrader for the treatment of the treatment of human cancers and other human diseases in which STAT3 plays a key role." [DOI:10.1158/1538-7445.am2024-3881]; target: "Taken together, (UM-STAT3-1218) is a highly promising STAT3 degrader for the treatment of the treatment of human cancers and other human diseases in which STAT3 plays a key role." [DOI:10.1158/1538-7445.am2024-3881]; developer: "1University of Michigan, Ann Arbor, MI." [DOI:10.1158/1538-7445.am2024-3881]; modality: "Discovery of highly potent, selective and efficacious STAT3 PROTAC degraders capable of achieving long-lasting tumor regression" [DOI:10.1158/1538-7445.am2024-3881]; stage: "Impressively, a single dose of (UM-STAT3-1218) at 3 mg/kg achieves complete and long-lasting tumor regression in multiple xenograft tumor models without any signs of toxicity." [DOI:10.1158/1538-7445.am2024-3881]