Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
umbilical cord artery-derived perivascular stem cells
- Development stage
- Unknown
- Lead developer
- The First Affiliated Hospital of Zhengzhou University
- Modality
- Stem Cell Therapies → Cell Therapies
- Administration
- Intramuscular
01
Overview
Umbilical cord artery-derived perivascular stem cells (UCA-PSCs) are a specialized population of mesenchymal-like stem cells isolated from the perivascular niche (the area surrounding the blood vessels) of the human umbilical cord artery. These cells are characterized by their high proliferative capacity, multi-lineage differentiation potential, and potent paracrine activity. In the context of regenerative medicine, particularly for Critical Limb Ischemia (CLI), UCA-PSCs are employed to stimulate angiogenesis and tissue repair. They function primarily by secreting a suite of pro-angiogenic and cytoprotective factors—including vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF)—which promote the formation of new capillary networks and improve blood perfusion in ischemic tissues. Additionally, they exhibit immunomodulatory properties that help mitigate inflammatory damage in the clinical target area.
- Other names
- Umbilical cord artery perivascular stem cellsUCA-derived perivascular stem cells
Beyond the preview
Go deeper on umbilical cord artery-derived perivascular stem cells.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on umbilical cord artery-derived perivascular stem cells.