Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
umbilical cord blood transplantation + interleukin-2
- Development stage
- Unknown
- Lead developer
- Masonic Cancer Center
- Modality
- Stem Cell Therapies → Cell Therapies, Cytokines & Interferons → Recombinant Proteins and Enzymes
- Administration
- Intravenous, Subcutaneous
01
Overview
This therapeutic protocol involves the transplantation of two units of T-cell depleted umbilical cord blood (UCB) in combination with the administration of Interleukin-2 (IL-2). Developed by the Masonic Cancer Center at the University of Minnesota, the treatment is specifically evaluated for patients with refractory acute myeloid leukemia (AML). The strategy aims to maximize the expansion and functional maturation of donor-derived natural killer (NK) cells in vivo. By providing IL-2 both during the activation of one UCB unit and as a post-transplant systemic therapy, the protocol seeks to enhance the graft-versus-leukemia (GVL) effect, particularly through the 'education' of NK cell progenitors contained within the UCB graft.
- Other names
- Double UCB with IL-2T-Cell Depleted Double UCB With Post Transplant IL-2UCB + IL-2
02
Targets
IL-2R (Interleukin-2/interleukin-15 receptor complex)
Beyond the preview
Go deeper on umbilical cord blood transplantation + interleukin-2.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on umbilical cord blood transplantation + interleukin-2.