Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
umbilical cord mesenchymal stem cells + collagen scaffold
- Development stage
- Unknown
- Modality
- Implantable Hydrogels → Hydrogel Systems → Drug Delivery Systems, Implantable Devices → Device-based Delivery → Drug Delivery Systems, Stem Cell Therapies → Cell Therapies, Injectable Hydrogels → Hydrogel Systems → Drug Delivery Systems
- Administration
- Surgical Implantation, Intrauterine, Topical, Intralesional
01
Overview
A combination therapy consisting of human umbilical cord-derived mesenchymal stem cells (UC-MSCs) and a collagen scaffold. UC-MSCs are multipotent stromal cells isolated from the umbilical cord, known for their high proliferative capacity, low immunogenicity, and ability to differentiate into various cell types. The collagen scaffold serves as a biocompatible matrix that provides structural support and enhances cell delivery to target tissues. This combination is designed for regenerative medicine applications; it promotes tissue repair through paracrine signaling (secretion of growth factors and cytokines), immunomodulation, anti-apoptotic effects, and direct differentiation into local cell types. Preclinical studies have shown efficacy in endometrial regeneration (restoring fertility after intrauterine adhesions) and spinal cord injury (promoting neurological recovery). The mechanism involves both the physical support of the scaffold for cellular engraftment and the biological activity of UC-MSCs in modulating inflammation, promoting proliferation of endogenous cells, inhibiting apoptosis, supporting angiogenesis, and remodeling extracellular matrix[1][2].
- Brand names
- NeuroRegen scaffold
- Other names
- UC-MSCs + collagen scaffoldhuman umbilical cord-derived mesenchymal stem cells loaded on collagen scaffoldCS/UC-MSCs
02
Targets
PDCD1 (Programmed cell death protein 1 receptor)
Beyond the preview
Go deeper on umbilical cord mesenchymal stem cells + collagen scaffold.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on umbilical cord mesenchymal stem cells + collagen scaffold.